hoods, biological safety cabinets, filter dryers, and other equipment periodically
due to corrosion following repeated exposure to bleach disinfectant solutions.
Substituting NaDCC for bleach can reduce the frequency of replacement of expensive equipment incurring a cost savings while maintaining the disinfection level
required for product manufacturing. This suggests using a NaDCC solution in
place of bleach as part of a disinfectant rotation.
1. Maillard, J-Y. “Bacterial target sites for biocide action.” J Appl Microbiol 2002;
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332 (1): 63–9. doi: 10.1006/abbi.1996.0317. PMID 8806710.
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by hypochlorous and hypobromous acids: insights into the mechanism of lysis.”
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of chlorine as a water disinfectant.” J. Am. Water Works Assoc. 40: 1051–1061.
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Sulfhydryl Enzymes as the Basis of the Bactericidal Action of Chlorine.” Journal of
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Ull-mann’s Encyclopedia of Industrial Chemistry, 2005, Wiley-VCH, Weinheim. ISBN
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11. NaDCC EPA label: http://www.epa.gov/pesticides/chem_search/ppls/071847-
12. Bleach EPA label: http://www.epa.gov/pesticides/chem_search/ppls/005813-
Jay C. Postlewaite, Ph.D., is the Senior Technical Advisor at Texwipe, an ITW
Company. He has held technical positions in global regulatory service, research, manufacturing, and product development. His current research is focused in the cleanroom
consumables and contamination control markets.
Wendy Hollands, MBA, is Business Development Manager at Texwipe, an ITW
Company. She has managed multiple cleanroom consumable product lines and specializes in sterile product lines including wipers, pre-wetted wipers, swabs, and sterile
Figure 4. The photograph above shows the coupons exposed to typical use concentrations of 1: 10 bleach and 1,000-ppm NaDCC solutions
at the end of the study. Note the discoloration and corrosion of the
304L and 316 1: 10 bleach solution coupons.
Figure 5. The photograph above shows the coupons exposed to
similar active chlorine concentrations of 1: 50 bleach and 1,000-ppm
NaDCC solutions at the end of the study. Note the discoloration and
corrosion of the 304L and 316 1: 50 bleach solution coupons.