Facility Profile: Pharma Tech
Pharma Tech Industries, a pharmaceutical contract manufacturer and packager of pow- der products, recently introduced a high- speed bottling line for the production of Rx,
OTC, and nutritional ingestible products at its
facility in Union, Mo. The bottling line is housed
in a new, specially-built ISO 8 Class 100,000 controlled environment designed for non-sterile Rx
pharmaceutical-grade oral products. All equipment is of modular, quick-change design to enable
minimal downtime between campaigns.
Controlled Environments spoke with Tee
Noland, Chairman and CEO of Pharma Tech
Industries, about this cleanroom facility addition.
Who designed/built the new cleanroom? What
was the cost?
Designed by Alan Alewine with architectural
services provided by Bates & Associates Architects
of Springfield, Mo., and mechanical engineering
design completed by Design Mechanical Inc. of
Chesterfield, Mo. The cost was $1.5 million.
How long did construction take? Where did
production take place during the construction
Construction took eight months. Production
took place on a slower existing line until construc-
tion was complete.
What’s the square footage of the cleanroom area?
What about other areas like a gowning area/ante
room? How big is the overall facility?
Facility is 55,200 square feet; gowning and
airlock is 441 square feet; processing is 3,146
square feet; secondary case packaging is 1,715
square feet; 428 square feet of equipment cleaning room.
How does the new facility differ from your previ-
The new facility separates the filling process
into rooms or cells to reduce risk of contamina-
tion and allows each cell to support the output of
the high speed line.
Secondary packaging line
at Pharma Tech Industries’
facility in Union, Mo.
units from production
the line includes premium
bundling, and casepacking
Image: Pharma Tech