Bischof + Klein Adds Production
Cells to Class 5 Cleanroom
Bischof + Klein, a packaging and film specialist
based in Lengerich, Germany, has added additional
production cells to its Class 5 cleanroom. The company offers flexible packaging solutions for medical
products and pharmaceuticals in this purity class.
The cleanroom production facility has been
extended to cover over 8,800 ft². The production
cells, including a module with a high-performance
automatic punching machine, are connected to an
intermediate warehouse. This machine produces
single- and two-ply Tyvek cover sheets for the
disposable syringe industry. The adjacent packaging line enables the bundle’s initial protective
packaging to be applied fully automatically. The
closed-loop cleanroom chain includes a laboratory
as well as lines for extruding polyethylene films and
for converting sacks and bags. The personnel air
lock has also been extended.
Materion Breaks Ground on Class
Materion Barr Precision Optics & Thin Film
Coatings has initiated the construction of a 3,000
ft2 Class 1,000 cleanroom outfitted with infrared
coating chambers and 3D patterning equipment.
The work cell will enhance Materion’s capability to
manufacture low-defect coatings in high volume
for the infrared wafer level, defense, and consumer
The Wafer Level Coating Cell, located at
Materion’s facility in Westford, Mass., is designed
to be self-contained with a semiconductor manufacturing layout to handle 200 mm wafers. The
multi-million dollar investment will assist in decreasing the cost of uncooled micro bolometer detectors and ultimately facilitate major growth throughout the commercial infrared camera industry. The
Wafer Level Coating Cell enhances competencies
across many other technologies such as gesture
control filters, arrays, and gas sensing filters.
Completion of the work cell is expected in
the third quarter of 2013 and will include a 3D
photolithography deposition tool, semiconductor
wet etch and alignment processing tools, semi-automated inspection tools, and several custom-designed high-volume 200 mm coating deposition
chambers. The long-range plan foresees a total
of 20,000 to 40,000 wafers per year when fully
built out. Initial work will be composed of multiple
volume production lines along with current projects aimed at the defense, commercial infrared,
and consumer electronics markets. In addition,
Materion is continuing to invest in its coating technology for the next generation micro-bolometer
devices (less than 12 micron) and plans to unveil
this new technology in 2014.
Materion Barr Precision Optics & Thin Film
Coatings provides technologies including optical
filters, filter arrays, lens coatings, and optical thin
film component assemblies. Markets are composed of life sciences and medical, commercial,
defense, thermal imaging, automotive, and space,
science, and astronomy industries.
Catalent Pharma Opens Single-Use Biomanufacturing Center
Catalent Pharma Solutions, a provider of drug and
biologic development services, delivery technologies, and supply solutions, has opened its biomanufacturing Center of Excellence in Madison, Wis.
The new facility will quadruple Catalent’s current
biologics manufacturing capacity, allowing the
company to extend its offerings in the sector while
enhancing the efficiency and output of its GPEx
cell line engineering technology as well as other
mammalian cell lines.
The official opening follows Catalent’s acquisition of an exclusive license to market Redwood
Bioscience’s SMARTag precision protein-chemi-cal engineering technology for the development
of advanced antibody drug conjugates (ADCs).
Redwood’s site-specific protein modification and
linker technologies enable the generation of homogenous bioconjugates engineered to enhance potency, safety, and stability. Catalent’s GPEx cell line
expression system is intended for the rapid development of stable, high-yielding cell lines, and a broad
range of analytical and fill-finish services.
Designed for flexible cGMP production, from
10 up to 1,000 L, and non-GMP production up to
250 L, the facility features extensive use of single-
use technologies and unidirectional flow to greatly
reduce cross-contamination risk. Manufacturing is
supported by integrated analytical, formulation devel-
opment and viral clearance capabilities, small-scale
and large-scale process development laboratories,
and separate microbiology and quality control func-
Wayne State University Opens
Cleanroom Lab for R&D
and diversify micro-technology
research at its multimillion dollar Nano Fabrication
Core Facility (nFab). The cleanroom lab, which was
originally built to focus on automotive applications,
has been home to a broader set of nanotechnology
research and development by WSU faculty and students. WSU has re-launched the lab and opened it
to researchers, students, and companies throughout
the region, who would otherwise not have access to
the rare microfabrication environment, with a valuation exceeding approximately $12 million.
The nFab lab, located in the College of
Engineering, was originally established in 2002
thanks to a major contribution from Delphi. Its
mission is to create devices that benefit humanity.
The lab provides researchers with three distinct
microfabrication services: deposition (the addition
of materials), lithography (the defining of materials),
and etching (the removal of materials). Cutting-edge processes and equipment include a high-temperature furnace, low-pressure chemical vapor
deposition (LPCVD), E-beam evaporator, sputtering, photolithography, isotropic wet or dry etching,
anisotropic wet or dry etching, and metal lift-off.
Some of Wayne State’s faculty members are
utilizing the lab for projects that include retinal processors that cause less tissue irritation and more
comfortable wearable health-monitoring devices,
balloon catheters, and stents; environmental sensors for preventing invasive species in the Great
Lakes; a chronic neural prosthesis using high-capacity graphene electrodes and biodegradable
silicon support to treat a variety of neurological
illnesses; the development of micro-electrochemi-cal electrodes for neurological research that may
have significant implications for those battling